We’re providing updates on the COVID-19 situation for the UK drug discovery community. Our aim is to help the community during this challenging time and also highlight important work and resources.
Samples for COVID-19 research
The UKCRC Tissue Directory and Coordination Centre (TDCC) is coordinating efforts to help find human sample resources that are available to support research into COVID-19.
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COVID-19 Open Research Dataset Challenge (CORD-19)
In response to the COVID-19 pandemic, the White House and a coalition of leading research groups have prepared the COVID-19 Open Research Dataset (CORD-19). CORD-19 is a resource of over 45,000 scholarly articles, including over 33,000 with full text, about COVID-19, SARS-CoV-2, and related coronaviruses. This freely available dataset is provided to the global research community to apply recent advances in natural language processing and other AI techniques to generate new insights in support of the ongoing fight against this infectious disease.
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The COVID-19 HPC Consortium
The COVID-19 HPC Consortium encompasses computing capabilities from some of the most powerful and advanced computers in the world. We hope to empower researchers around the world to accelerate understanding of the COVID-19 virus and the development of treatments and vaccines to help address infections. Consortium members manage a range of computing capabilities that span from small clusters to some of the very largest supercomputers in the world.
Resources available for COVID-19 HPC Consortium request:
- U.S. Department of Energy (DOE) Advanced Scientific Computing Research (ASCR)
- U.S. DOE National Nuclear Security Administration (NNSA)
- U.S. National Science Foundation (NSF)
- NASA High-End Computing Capability
- Amazon Web Services
- MIT/Massachusetts Green HPC Center (MGHPCC)
- Rensselaer Polytechnic Institute
- IBM Research
Rapid Assistance in Modelling the Pandemic: RAMP
This call for assistance is addressed to the wider modelling community (including data analytics) in academia and industry. Our initial focus is on the UK community but this is an international emergency and we welcome contributions from non-UK based scientists, while realizing that they might wish to prioritize any similar initiative in their own countries.
Qualified researchers, willing to devote time to RAMP, are asked to take the following steps:
- if you are a Group Head, Principal Investigator or Team Leader, please canvas your group or team of colleagues, research students and postdocs (or the industry equivalent to those roles) and submit a joint response for the group or team using the response form provided.
- if you are a postgraduate student or postdoc, please canvas your Advisor / PI / Group Head / Team Leader as appropriate and ask them to submit a team-level response as in (i).
- only if you are a sole researcher, for instance a recently retired academic, please fill out the form in your own right.
The STFCs – Central Laser Facility (CLF) is inviting rapid access proposals to their facilities
These include a comprehensive range of optical microscopy instruments and techniques including super-resolution (PALM/STORM, SIM, and STED, including STORM at cryogenic temperatures), single molecule imaging and tracking, light sheet microscopy, FRET-FLIM, and optical trapping/tweezers. They also offer a Zeiss Crossbeam cryo FIB-SEM with “slice and view” capability.
In addition, the Diamond Light Source are also offering priority rapid access for groups who require synchrotron instrument time for projects directly related to SARS-CoV-2 viral proteins.
This call is open to all researchers in academia or industry worldwide, this is a rolling call with no deadline; proposals will be evaluated on receipt, and those that pass an initial feasibility and safety check will receive a light touch, rapid turn-around peer-review by members of our Facility Access Panel. There are no charges for access to the facility for successful applicants.
Clinical Practice Research Datalink (CPRD) is expediting the processing of protocols related to COVID-19 research