× Medicines Discovery Catapult

We’re looking for SMEs or academics wanting to test their innovations, hypotheses or cell models in organ on a chip (OOAC) or micro-physiological systems.

OOAC technology allows 3D human organs to be linked by microfluidic channels. It’s possible to re-create functionality from many organs including lungs, kidneys, heart, brain and skin. The added value in this approach is to enable microfluidic flow into single cell models, or connect multiple models together recapitulating relevant biological interactions and physiological communication.

  • Could working with us boost your current research?
  • Have you considered exploiting the potential of OOAC technology?
  • Do you have cell models that could be connected into OOAC to add value?
Photo of organ on a chip
Tissuse organ on a chip technology

How can organ on a chip technology address your medicines discovery challenge?

Organ on a chip technology improves biological relevance,  saves vital time, resource and money, as well as potentially reducing the number of failed trials and disappointments further down the line.

These sophisticated models of human organ systems better mimic what happens when patients receive drug molecules; providing patient relevant data, enabling risk-free biomedical testing and likely reducing the need for animal disease models.

Our offering

  • Established commercial OOAC platforms and a host of cutting edge detection technologies
  • Willingness to co-develop relevant human cell models in OOAC systems to meet the needs of the UK SME community
  • Expert advice on the most appropriate models and endpoints to test hypotheses
  • Experience in the industrialisation and validation of cell model systems to pharmaceutical industry standards
  • Ability to test candidate drugs in industry validated models of human relevance, increasing the chance of success in the clinic
  • Generate data that will enable you to select, optimise or withdraw drugs at earlier stages of drug discovery, de-risking programmes and potentially reducing reliance on expensive animal disease models

Working with us

We work with our partners in a range of different approaches:

  • Shared risk and reward
  • Joint grant applications for collaborative R&D funding
  • Contracted fee-for-service projects
Illustration of a heart on a chip