Blogs

Blogs written by our own experts or selected members of the drug discovery community.





Blogs
14 October 2020
Strategies for target and pathway engagement in cellular assays

Importance of understanding target engagement





Blogs
14 October 2020
Go Native… Characterising therapeutic effect in primary cellular models

The advantages and disadvantages of in vitro cell models using primary cells


Blogs
07 October 2020
Understanding PK/PD using pre-clinical models

Lessons for efficacy studies at AxisBio


Blogs
07 October 2020
Principles and modelling of pharmacokinetic and pharmacodynamic relationships

How PK-PD modelling can be applied in early stage drug discovery


Blogs
30 September 2020
Designing formulations for preclinical and early stage clinical studies

How the formulation of a compound can be optimised to maximise dose and absorption in preclinical studies


Blogs
30 September 2020
IKKɛ/TBK1

A case study of approaches to turning fragment hits into drug candidates


Blogs
30 September 2020
Synthetic chemistry aspects of drug discovery and early development projects

The different skills required from early drug discovery to development phases


Blogs
23 September 2020
In-silico drug design

What to do, what not to do


Blogs
23 September 2020
Optimising ADME and PK properties

Common mistakes made and how to identify and resolve the key issues






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