Mass Spectrometry (MS) is one of the most powerful and flexible analytical technologies in modern drug discovery.
We support innovators with expert advice, novel workflow development and high-throughput analysis using state-of-the-art MS platforms.
Whether you are looking at drug distribution, uncovering biomarkers or tracing metabolic activity, our team can help you generate the right data faster.
Our Mass Spectrometry team will help you navigate the complex space of current methods and instrumental platforms, offering solutions from early discovery and preclinical evaluation through to the clinic to advance your project.
We provide lab services ranging from sample preparation for MS application to analysis and data processing.
Biomarker discovery strategy
We combine ultra-high-resolution MS with computational pipelines to implement biomarker discovery strategies. Our workflows integrate multi-omics (proteomics, metabolomics, and lipidomics) data to identify, verify and quantify biomarkers of disease and therapeutic response.
Biodistribution studies
We use Mass Spectrometry Imaging (MSI) to assess drug and molecular ions distribution across tissues and organs. These methods provide spatial and molecular insight to support pharmacokinetic and pharmacodynamic studies.
Protein analysis – Proteomics
Our MS approaches include stability, aggregation, and post-translational modifications. We support therapeutic programmes with detailed analysis of intact proteins and their interactions.
Metabolomics and lipidomics
We deliver targeted and untargeted metabolomics and lipidomics studies using high-resolution MS platforms. These assays uncover cellular changes, elucidate pathway activity, and support mechanism-of-action investigations.
Screening assays
We develop scalable assays for compound screening. These high-throughput workflows allow detection of enzymatic activity, target engagement, and cellular response, particularly where traditional readouts are limited.
Bioinformatics
We use dedicated bioinformatics pipelines and statistical tools to interpret complex datasets from Mass Spectrometry and multi-omic platforms. Our team helps translate large-scale molecular data into actionable insights that support target discovery, biomarker validation, and pathway analysis.
MS Platforms: Thermo Orbitrap Astral™, Thermo Exploris™ 240, Waters Synapt G2-Si, Waters Xevo TQ-XS.
Chromatography: UHPLC, nano-HPLC, high/micro/low flow setups.
Ion sources: ESI, nESI, DESI, AP-MALDI.
“Mass Spectrometry is an immensely powerful tool in bioanalysis and medicines discovery. Our MS laboratories support everything from small molecule analysis to spatial biomarker discovery.
Our team is here to help you unlock richer, faster insights across the discovery pipeline.”
Dr Bruno Bellina, Lead Scientist
We will help you to choose the right analytical approach to generate high-quality, decision-driving data, whether you are exploring for novel biomarkers, target engagement, or biodistribution.
Fill in the form today and speak to us to see how we can help advance your drug discovery project.