End-to-end in vitro and in vivo evaluation of radiopharmaceuticals in patient-derived models

AACR 2026 Poster | Targeted radionuclide therapy (TRT) with alpha and beta emitters provides a precise cancer treatment approach that improves outcomes while limiting systemic toxicity.

The development of new radiopharmaceuticals relies on robust in vitro and in vivo assays to assess target specificity, pharmacokinetics, biodistribution, resistance mechanisms, and therapeutic index.

Our results show that combining radiochemistry expertise with clinically relevant patient-derived models improves characterisation of novel radiopharmaceuticals and strengthens the predictive power of preclinical studies, ensuring new therapies align with clinical needs.

Meet the team at AACR 2026 at Booth 1418, Hall C (Ground Level).


R&D Consultancy - An image of a scientist working on radiopharmaceutical research in a laboratory



View the poster here







News
22 September 2026
New standardised, contemporary strain panels address a long-standing barrier in AMR research

PACE (Pathways to Antimicrobial Clinical Efficacy) and the UK Health Security Agency (UKHSA) have released five new contemporary antimicrobial resistance (AMR) strain panels, giving innovators worldwide a resource to test novel therapeutics and diagnostics against today’s resistance patterns.


new board appointments
News
15 September 2026
Medicines Discovery Catapult appoints global life science and commercialisation leaders to its Board of Directors

New appointments support MDC’s mission to turn drug discovery into commercial breakthroughs.


News
10 September 2026
Inspiring the next generation: Medicines Discovery Catapult scientist contributes to children’s science book 

Dr Emma Jones, a Lead Scientist in in vitro Neurobiology at Medicines Discovery Catapult (MDC), has contributed to a new children’s book celebrating the diversity of careers in science.





Medicines Discovery Catapult