× Medicines Discovery Catapult

PROTAC Assays – Successfully measuring Protein Degradation

PROTAC (PROteolysis TArgeting Chimera) is one of the hottest topics in drug discovery today as it is a highly promising new approach to targeted therapy. It offers several advantages over traditional occupancy-based drugs, with a potential to target the ‘undruggable’ proteome. Read our blog below to learn more about PROTAC and some assays that can […]

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Meet Juliana Maynard – Lead Scientist

Which team do you work in and what does that team do? I work in Discovery, specifically the pre-clinical imaging team. We are a team of 4 – there’s me, Neil Gingles, Benedetta Arno and Gemma Forrest– it’s a great team! What’s your role within your team? I engage with our collaborators to understand what […]

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Meet Sarah Brockbank – Lead Scientist

Which team do you work in and what does that team do? I work in Virtual R&D team. Our remit is to support clients drug discovery projects by reviewing their project plans and data, challenging it, and providing proposals to take them to the next stage. We also work closely with external experts within our […]

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Meet Duygu Yilmaz – Senior Scientist

Which team do you work in and what does that team do? I work in the Target Engagement & Validation team – our goal is to help companies develop better drug molecules that have meaningful effects in the clinic. We design experiments to demonstrate that a drug molecule engages with its molecular target and affects […]

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Meet Joanne Hartley – Senior Scientist – Biosamples

Which team do you work in and what does that team do? I work on samples with Helen Hind, which is part of our Discovery team. The team’s remit is to help companies locate and access clinical samples for use in their research. What’s your role within your team? I support many of the team’s […]

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Application of AI and data science to extract value from Real-World Data (RWD)

In medicine, Real World Evidence (RWE) is derived from Real-World Data (RWD) and is the evidence regarding the clinical use and potential benefits or risks of a medical product. Essentially RWD can mean any data that is collected outside of a clinical trial and can relate to the health of the patient and/or the delivery […]

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Meet Helen Hind – Biosamples Lead

Which team do you work in and what does that team do? I lead the Samples capability which is part of our Discovery team. Our remit is to support SMEs in accessing clinical samples, which they often require to progress their R&D assets. Based on previous feedback we’ve received from the UK life sciences sector, […]

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Meet Rachel Lawless – Grants Officer

Which team do you work in and what does that team do? I work in the Grants team – our role is to provide funding help and guidance to our business partners. This includes scoping out grant opportunities, helping with grant writing, and connecting partners who can compliment each other to ensure projects are run […]

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Guiding health researchers through the approvals needed to obtain NHS data

The MRC Regulatory Support Centre have developed The Health Data Access Tool Kit to help health researchers access NHS data. Programme Manager, Alex Bailey explains the thinking behind it. The researcher’s problem: I can’t get hold of the data I want We are all governed by a surfeit of laws, regulations and policies in our […]

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