× Medicines Discovery Catapult

Alderley Park Conference Centre

Date(s) 26/09/2019     Time All Day


Following the success of our inaugral meeting in 2018, ELRIG is pleased to invite you to the 2nd Discovery Technologies meeting to be held at Alderley Park, Macclesfield, UK on September 26th, 2019. This ELRIG meeting, which will be run in collaboration with Alderley Park, will focus on novel and emerging technologies that are improving the efficiency and success rates in the drug discovery process. The two main themes of the conference will be the application of imaging techniques in drug discovery and approaches and technologies used to address early safety assessment within the pharmaceutical industry.

For 2019 the conference will include two parallel sessions:

1. Imaging Techniques in Drug Discovery

This session will focus on the application of imaging techniques in drug discovery, including in vitro 3D imaging approaches, MS imaging and in vivo imaging applications. The use of imaging in drug discovery is becoming increasingly routine to inform decisions with applications ranging from high throughput screening to clinical assessment. This session will explore the use of imaging in fields including investigating disease specific pathophysiology’s, characterising the pharmacokinetics / pharmacodynamics of molecules and defining disease specific therapeutic endpoints.

2. Approaches and technologies to address early safety assessment

Failure rates in drug development due to adverse safety profiles are still a major problem in the industry. As a result, the pharmaceutical industry is increasingly focused on the characterisation of the safety profile in early discovery to de-risk and optimise compounds prior to further development. This session will look at approaches used to assess target organ toxicity in a discovery setting focusing on areas such as drug induced livery injury (DILI), cardiac safety assessment and immunosafety profiling of large molecules. Technology advances in this field, such as in iPSC derived and organ-on-a-chip models, will be discussed.

Malcolm Haddrick, Lead Scientist for Medicines Discovery Catapult is a Conference Director for this event.

 

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