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Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans

Read the article at Nature Communications

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Structural and Functional View of Polypharmacology

Read the article at Nature Scientific Reports

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Target Identification of Mycobacterium tuberculosis Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach

Read the article at Frontiers in Pharmacology

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The importance of triaging in determining the quality of output from high-throughput screening

Read the article at Future Medicinal Chemistry

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The ELF Honest Data Broker: informatics enabling public–private collaboration in a precompetitive arena

Read the article at Drug Discovery Today

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A global view of structure–function relationships in the tautomerase superfamily

Read the article in the Journal of Biological Chemistry

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Identification of Allosteric Modulators of Metabotropic Glutamate 7 Receptor Using Proteochemometric Modeling

Read the article at the Journal of Chemical Information and Modeling

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Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites

Read the article in Nucleic Acids Research

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Chapter One – Atlas of the Radical SAM Superfamily: Divergent Evolution of Function Using a “Plug and Play” Domain

Read the article at Methods in Enzymology

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