Blogs

Blogs written by our own experts or selected members of the drug discovery community.





Blogs
07 October 2020
Principles and modelling of pharmacokinetic and pharmacodynamic relationships

How PK-PD modelling can be applied in early stage drug discovery





Blogs
30 September 2020
Designing formulations for preclinical and early stage clinical studies

How the formulation of a compound can be optimised to maximise dose and absorption in preclinical studies


Blogs
30 September 2020
IKKɛ/TBK1

A case study of approaches to turning fragment hits into drug candidates


Blogs
30 September 2020
Synthetic chemistry aspects of drug discovery and early development projects

The different skills required from early drug discovery to development phases


Blogs
23 September 2020
In-silico drug design

What to do, what not to do


Blogs
23 September 2020
Optimising ADME and PK properties

Common mistakes made and how to identify and resolve the key issues


Blogs
23 September 2020
In vivo imaging to understand the biodistribution of a candidate compound

How imaging technologies can be used to establish the biodistribution and accumulation of the compounds in vivo


Blogs
16 September 2020
Where can CryoEM be positioned in Medicines Discovery?

How the emerging field of CryoEM can be applied to generate structural information for a wide range of targets


Blogs
16 September 2020
Make the molecules that matter

How structure based and ligand based software tools can be used to virtually discover, design and optimise compounds






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