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News, blogs, events, reports and more

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Blogs
21 October 2020
Challenges and Opportunities of Complex Cell Models for Toxicity Testing

Using complex cell models in early de-risking strategies and toxicity testing





Blogs
14 October 2020
Use of preclinical models to deliver proof of concept efficacy

The advantages and disadvantages of in vitro cell models using primary cells


Blogs
14 October 2020
Strategies for target and pathway engagement in cellular assays

Importance of understanding target engagement


Blogs
14 October 2020
Go Native… Characterising therapeutic effect in primary cellular models

The advantages and disadvantages of in vitro cell models using primary cells


Blogs
07 October 2020
Understanding PK/PD using pre-clinical models

Lessons for efficacy studies at AxisBio


Blogs
07 October 2020
Principles and modelling of pharmacokinetic and pharmacodynamic relationships

How PK-PD modelling can be applied in early stage drug discovery


News
06 October 2020
Oncimmune and Medicines Discovery Catapult awarded UK Government funding for development of an Infectious Disease research tool for use in COVID-19

Validated research tool to be used to predict disease severity and individual therapeutic response to COVID-19 in aid of rapid vaccine and drug development.


Blogs
30 September 2020
Designing formulations for preclinical and early stage clinical studies

How the formulation of a compound can be optimised to maximise dose and absorption in preclinical studies






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Medicines Discovery Catapult