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Dosimetry









Dosimetry to optimise clinical development

We deliver quantitative, regulatory aligned dosimetry using predictive human dosimetry from pre-clinical data and multi‑time point biodistribution data.

Our approach follows FDA, EMA and MHRA guidance for radiopharmaceuticals, giving innovators the confidence to progress toward IND and first‑in‑human studies.



























What we deliver 

  • Organ level absorbed dose estimates.
  • Voxel based and MIRD methods.
  • Multi‑time point biodistribution integration.
  • Human dose extrapolation.
  • Safety margin assessment.
  • PK/PD and toxicity correlation.

One team. One workflow. One standard of quality.




Why work with us? 

  • In-house specialisms: Deep radiopharmaceutical biology expertise.
  • Built for reliability: Predictive human dosimetry from pre-clinical data.
  • Regulatory‑ready: ISO 45001 certified and licensed for alpha & beta emitters.
  • Full-stack in-house capability: Integrated biodistribution and imaging.
  • Global credibility: Our environment is built for regulatory credibility, whether your next step is the FDA, EMA or MHRA.
  • Trusted by innovators: Translation enabled using clinically validated software.

If you need dosimetry that stands up to regulators and investors, you need us.


























World-class minds for RPT discovery and development

In the complex landscape of radiochemistry and translational imaging, the difference lies in the expertise behind the science.

Our team comprises industry-leading specialists across preclinical services and radiopharmaceuticals, dedicated to bridging the gap between early discovery and clinical success.

Meet the experts who turn sophisticated data into actionable therapeutic insights.

Explore our scientific expertise

Case study: 77Lu dosimetry

Brief: Determine human organ dose exposure for IND planning.

We delivered: 

  • Multi‑time point biodistribution.
  • Human organ dose extrapolation.
  • Safety margin analysis.

Outcome: IND‑enabling package strengthened and timelines protected.


























Start your project 

Ready to accelerate your dosimetry project? 

Our experts are here to support your journey from concept to clinic. Contact our team to discuss a tailored solution. 

Speak to the team, we’ll scope your project and get you moving fast. 




Expertise in radiolabelling

With gamma, beta and alpha-emitting radiometals of small molecules (e.g., FAPI, PSMA), peptides, proteins and other biologics containing chelators such as DOTA, DOTAM, Macropa, and DFO/DFO*. Experience in a variety of purification methods (e.g., ultrafiltration, SPE), QC analysis (HPLC, ITLC, gamma spectrometry), and conjugation techniques. 

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Visualising impact in real-time

Utilising CDX and PDX models to deliver high-resolution longitudinal tumour growth inhibition (TGI) data and PK/PD analysis. 

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Mapping the path to the target

Quantitative time-course activity analysis across 15+ organ systems using PET, SPECT and CT imaging, EBRT, US, Gamma counting and PK modelling. 

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Ensuring safety and maximising therapeutic windows

Precise calculation of absorbed doses (Voxel/MIRD) to provide reliable preclinical-to-clinical dose extrapolation. 

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The “See it, Treat it” advantage

Strategic pairing of diagnostic/therapeutic isotopes (e.g. 89Zr and 177Lu) to build companion imaging and patient-selection strategies. 

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Early-stage de-risking

High-throughput screening for affinity, internalisation, and stability to identify lead candidates faster. 

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Deep-dive tissue validation

Detailed cellular phenotyping through high-resolution autoradiography, gamma counting, and IHC correlation.

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We are ISO 45001 certified 

The world’s first international standard for occupational health and safety. The accreditation has been certified by Interface NRM, a UKAS and ASI–accredited certification body.











Medicines Discovery Catapult