Blogs

Articles written by our own experts or selected members of the drug discovery community.





Blogs
23 September 2020
In-silico drug design

What to do, what not to do





Blogs
23 September 2020
Optimising ADME and PK properties

Common mistakes made and how to identify and resolve the key issues


Blogs
23 September 2020
In vivo imaging to understand the biodistribution of a candidate compound

How imaging technologies can be used to establish the biodistribution and accumulation of the compounds in vivo


Blogs
16 September 2020
Where can CryoEM be positioned in Medicines Discovery?

How the emerging field of CryoEM can be applied to generate structural information for a wide range of targets


Blogs
16 September 2020
Make the molecules that matter

How structure based and ligand based software tools can be used to virtually discover, design and optimise compounds


Blogs
16 September 2020
Proteins, X-ray crystal structures, and how to get them

Generating good quality protein suitable for structural studies


Blogs
09 September 2020
Meet Gayle Marshall – Lead Scientist (Biomarkers)

Learn about Gayle’s journey from Biomarkers to the Lighthouse Lab


Blogs
09 September 2020
HIT ID screening – understanding why your target is key

A critical starting point for a drug discovery programme


Blogs
09 September 2020
Cell-based screening: Old dogs with new tricks

Generating good quality protein suitable for structural studies


Blogs
09 September 2020
Targeted compound libraries

How the emerging field of CryoEM can be applied to generate structural information for a wide range of targets






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