Accumulation of Bioactive Lipids in LPS-Induced Neuroinflammation Models: MSI Biomarkers

Irma Berrueta Razo; Hervé Boutin; Adam McMahon; Nicholas Lockyer; Philippa J Hart


Mass Spectrometry Imaging (MSI) was applied to the analysis of neuroinflammation models. We aim to identify active lipid species that accumulate during the inflammation process and the possible ion signatures associated with the presence of activated microglia cells. Multimodal imaging techniques were applied such as MALDI, DESI, TOF-SIMS and microscopy.

Created in collaboration with the University of Manchester for the Biomarkers UK event.

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