Human iPSC Derived Microglia Cell Assays

Kerry Shea, Emma Offer, Gayle Marshall, Rebecca Kelly, Emma Jones, Andrzej Rutkowski, Isabel Peset Martin and Peter Simpson


This poster describes the use of iPSC derived microglia to develop cell models to functionally characterise a range of phenotypic activities (cytokine release, phagocytotic activity and cell migration) in-vitro. The ability to measure these functions in a lab will allow us to expedite the development of more clinically predictive disease-relevant human cell models for a range of neurodegenerative diseases with the aim of identifying more effective treatments any improved model will bring.

This poster was created for ELRIG Drug Discovery 2021.

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