Efficient Intracellular Delivery of Nucleic Acids by NUVEC® Silica Nanoparticles

Aadarash Zia, Nisha Ponnappan, Duygu Yilmaz, Rebecca, Dominic Simpson, Isabel Peset Martin, Emily Offer, David Templeton, Robert Harris, Melody Janssen, Nigel Theobald and Lorna FitzPatrick

ELRIG Poster Efficient Intracellular Delivery of Nucleic Acids by NUVEC® Silica Nanoparticles

Efficient Intracellular Delivery of Nucleic Acids by NUVEC® Silica Nanoparticles:

In recent years, there has been a surge in the development of a more diverse range of therapeutic modalities to treat disease, initiating a shift from a drug discovery pipeline of largely small and large molecule medicines. This includes but is not exclusive to nucleic acid therapeutics. Although efficacious and target specific when inside the cell, limitations of delivery are restricting translation of therapeutic mRNA, siRNA and DNA to the clinic. Efficient Intracellular Delivery of Nucleic Acids by NUVEC® Silica Nanoparticles

This poster was created for ELRIG Drug Discovery 2022.

 

ELRIG Poster Efficient Intracellular Delivery of Nucleic Acids by NUVEC® Silica Nanoparticles