Radiopharmaceuticals represent a powerful and precise approach to cancer therapy, combining targeted biological delivery with radioisotopes.
In medical imaging, radiopharmaceuticals act as radioactive tracers, helping to diagnose disease more accurately. In therapy, they are designed to bind to cancer-specific markers, and deliver powerful targeted radiation, exactly where it needs to be.
We combine world-class radiochemistry capabilities and advanced imaging technologies to support the development, characterisation and clinical readiness of novel radiopharmaceutical agents.
Radiopharmaceuticals can be used to diagnose disease as well as to treat them. A radiopharmaceutical molecule has two key components: the radionuclide that emits radiation and the molecule that takes the radionuclide to the cancer tissue.
Radiopharmaceuticals can be used for diagnosis with PET and SPECT scanning allowing visualisation of body structures or metabolic activity, or they can be used as therapeutics delivering the radiation to the tissue and destroying the cancer tissue.
Radiopharmaceutical therapies (RPTs) are precision treatments that use radioisotopes to effectively target, diagnose and treat cancers. These therapies pair radioisotopes with tumour-targeting small molecules, peptides or antibodies, delivering a cytotoxic payload directly to cancer cells, while sparing healthy tissue.
Therapeutic radiopharmaceuticals hold such promise for how we treat diseases like cancer, because traditional chemotherapy and radiotherapy can affect both healthy and disease tissue, which can result in side effects. Radiopharmaceuticals are much more targeted, which means treatments are more effective and less toxic.
A further approach will combine diagnostic and therapy in one platform. Doctors can use a diagnostic to see and check if the drug binds to the tumour and then use the therapeutic version for treatment. This will help predict patient success and ultimately patient outcome.
Radiopharmaceutical therapies are injected into the bloodstream, binding to specific molecules on the surface of the cancer cell. Once bound they can deliver cell-killing doses of radiation that destroys the cancer cell from within.
Significant advances have been made in new treatments for cancer, including Stem Cell Therapies, Immunotherapy, DNA Sequencing, Personalised Vaccines, and now Radiopharmaceutical Therapy (RPT).
We are pioneering the development, evaluation, and translation of radiopharmaceutical therapies to effectively diagnose and treat cancers.
As a national Life Sciences service, our exceptional people combine their scientific, regulatory and operational expertise with the very best technology to deploy novel radiopharmaceutical therapies.
We can help support a seamless transition of your radiopharmaceutical into the clinic as we have a unique blend of scientific expertise and operational expertise in novel radiopharmaceutical agents.
We support the seamless development of radiopharmaceuticals from pre-clinical data through to clinical readiness.
Our team work with industry and academic partners to:
With state-of-the-art facilities and authorisation to handle a wide range of isotopes, we offer unique, integrated services to de-risk radiopharmaceutical development:
Our experts are here to support your radiopharmaceutical journey from concept to clinic.
Fill in the form today and speak to us to see how we can help advance your drug discovery project.