Investigation of Lipid Biomarkers in Amyotrophic Lateral Sclerosis Using Mass Spectrometry Imaging
The application of Mass Spectrometry Imaging (MSI) can be used for the investigation of lipid metabolism dysregulation. Preclinical mouse brain and spinal cord tissues were analysed prior to human tissue from patients with slow and fast ALS progression to assess the link between altered metabolism of lipids and the progression of ALS.Investigation of Lipid Biomarkers in Amyotrophic Lateral Sclerosis Using Mass Spectrometry Imaging